Hoda Ayurvedic Health Care Centre

  • Litchi consumption, particularly unripe fruit on an empty stomach, is linked to Acute Encephalitis Syndrome (AES) outbreaks in poor, rural areas of India, especially Muzaffarpur. • Malnutrition is a significant underlying risk factor for AES, with malnourished children being more vulnerable to the effects of litchi. • Unripe litchi contains compounds like hypoglycin A that can disrupt sugar metabolism, leading to severe hypoglycemia and potentially hypoglycemic encephalopathy. • AES cases spike during the litchi-harvesting season (May-June) among children aged under-5 to 15. • Skipping the evening meal and then consuming large quantities of litchi significantly increases a child's risk of AES-type hypoglycemic encephalopathy. • Well-nourished individuals can safely consume ripe litchi in normal amounts; the risk is concentrated in undernourished children eating unripe fruit on an empty stomach. • Preventive measures include ensuring children eat regular meals, especially an eve...

                   Refractory functional GI disorders are chronic, recurrent conditions lacking structural explanations on routine tests. • Common examples include Irritable Bowel Syndrome (IBS), Functional Dyspepsia, Functional Heartburn, and chronic functional nausea/vomiting/constipation. • These disorders often respond poorly to standard treatments due to braingut axis dysfunction. • Abnormal signaling between the gut and central nervous system leads to altered motility, hypersensitivity, and amplified pain. • Overlap of multiple functional GI problems in patients necessitates treatments that address more than one issue. • Psychosocial factors like stress, anxiety, and depression can perpetuate symptoms and reduce treatment efficacy. • Management should adopt a multimodal, biopsychosocial approach, combining pharmacotherapy with psychosocial support. • Neuromodulators and psychotropics, such as low-dose antidepressants (TCAs, SSRIs) ...